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Stacking Psychedelics For Seniors

Stacking Psychedelics for Seniors
Table of Contents

The practice of “stacking” psychedelics, or taking them in combination with other substances, is becoming increasingly popular among some individuals who believe that it can enhance the effects of these drugs. Some people stack psychedelics with supplements, such as vitamins or herbal remedies, in the belief that these substances can boost the effects of the drugs or provide additional benefits. Nevertheless, this practice has piqued interest, not only in young adults but in seniors as well.

Benefits of Taking Psychedelics

As medical and recreational use of cannabis grows all over the country, older adults are increasingly smoking cannabis or taking it in form of CBD supplements. There is remarkably little information on how CBD or THC affects seniors, although some anecdotal reports suggest that it may beneficial in lowering stress levels and treating anxiety.

Nowadays, medical researchers are starting to take a deeper look at the clinical implications of cannabis use by seniors. And it isn’t just cannabis that is taking the spotlight. Researchers at Johns Hopkins Medicine are taking a look into the therapeutic use of psychedelics such as psilocybin (one of the active ingredients in magic mushrooms) for treating a wide range of medical ailments, such as dementia, depression, PTSD, and anxiety.

Some Of The Most Popular Stacking Combinations For Seniors

  1. The Aztec Combo 

Among Indigenous people, mixing psychedelics with other non-psychedelic substances such as foods or drinks is not an uncommon practice. These are known as admixtures and are thought to enhance the psychoactive effects of the drug.

The most significant example of this practice is combining magic mushrooms with liquid cacao. This ancient combination used by the Aztecs of Mexico was known as “cacahua-xochitl,” meaning chocolate mushrooms. They also combined psychedelic mushrooms with honey and various flowers or herbs.

This practice was carried out because the Aztecs believed cacao offered health benefits, such as enhancing mood, which when combined with magic mushrooms improved the overall healing effect.

  1. Stamets Stacks

An infamous mycologist Paul Stamets developed a protocol for microdosing that he believes can improve both mental and physical health. Stamets Stack protocol consists of Lion’s mane, psilocybin, and niacin. According to him, it can improve neurogenesis – the ability to regenerate nerve cells, also it may potentially be used as a neuroprotective agent.  This is by far the most commonly used stacking protocol with 5 to 20 grams of Lion’s mane, 0.1 to 0.3 grams of Psilocybin mushrooms, and 100 to 200 milligrams of Niacin (B3).

  1. Lynx Stack

Lynx Stack is a special microdosing blend. It consists of Lion’s mane extract, Turkey tail extract, and psilocybin-containing mushrooms. The idea behind this stack is to take 100mg of each substance with the goal to improve brain function, immunity, and nutrient absorption. When combined, the compounds from these mushrooms improve your energy levels and elevate you every day during the protocol. There are no risks of visual or auditory hallucination, as the blend acts sub-perceptually. Lynx stack is considered a perfect low-dose blend.

  1. Other Combinations – Psilocybin with Cacao, Niacin, Lion’s Mane, and Syrian Rue

According to a recent study published in Scientific Reports in November 2021 on microdosing practices, adults who microdose psychedelics report an increase in motivation and lower levels of depression and anxiety compared to non-microdosers. Also more than 50% of participants reported stacking psychedelics with another substance.

The researchers confirmed that cacao is one of the most popular additions to psilocybin. The survey also revealed multiple other combinations, including.

Lions Mane Mushroom – a medicinal mushroom used in traditional Chinese medicine

Niacin – B3 vitamin that helps the body to turn food into energy

Syrian Rue – a plant native to the Mediterranean sea, used for its alleged stimulant and hallucinogenic effects.

What Health Benefits Can Seniors Expect?

One of the main benefits of microdosing psychedelics is that it allows individuals to experience the potential therapeutic benefits of these substances without the potentially negative effects of higher doses. While psychedelics can be powerful tools for personal growth and exploration, they can also cause anxiety and confusion. By taking small doses, individuals can avoid these negative effects while still experiencing the potential health benefits of psychedelics.

Stacking Psychedelics Seniors

In addition to these benefits, stacking psychedelics may also have other potential health benefits. For example, some studies have suggested that psychedelics may have anti-inflammatory effects, which could potentially be helpful for individuals with chronic pain or other conditions, combining it with other fungi such as Lion’s mane which is filled with antioxidants is a great and synergizing option. Additionally, psychedelics have been shown to have positive effects on mood and anxiety, which could be beneficial for individuals with mental health conditions such as depression or anxiety.

  • Reduce symptoms of anxiety and depression
  • Improve energy and stamina
  • Enhances creativity
  • Improves empathy and consideration for others
  • Promotes focus and learning abilities
  • Elevates mood
  • Act as a neuroprotective agent
  • Promotes neurogenesis

Are There Any Risks?

While microdosing is generally considered a safe practice, there may be some possible risks, especially for older adults. There are a lot of both good and bad anecdotal reports regarding psychedelics. However, there is not much scientific research done on seniors in particular so these claims may or may not be true.

Most studies exclude seniors. Older adults and younger folks might respond to drugs quite differently, this is a common issue with drug research. Another issue regarding the safety of stacking psychedelics for seniors is that many people in this age group are taking medications. For example, psychedelics can increase blood pressure and heart rate, and if you’re taking blood pressure medication, psychedelics might not be the right way to go. It’s always important to consult with your healthcare provider and see if it’s safe for you to consume psychedelics.

While the majority of psychedelics are illegal it can be potentially dangerous to obtain these substances from the streets, as they might be misinterpreted, or in some cases, other harmful chemicals may be added to the drug. It’s very important to get your product from a trusted and reputable source.


Seniors’ resources may be limited, however, some older adults chose to implement microdosing stack into their daily routine. Some of the most common stacks for seniors are psychedelics combined with lion’s mane, Syrian rue, cocoa, and niacin. It is believed that when stacked, psychedelics synergize with other non-psychedelic compounds, increasing the healing effects and overall well-being. Seniors who decide to stack will most likely feel the stress and anxiety fade away, also mood and creativity will significantly improve.

In addition, stacking psychedelics may improve neuroregeneration and act as a neuroprotective agent,which can be beneficial in treating conditions such as dementia. It’s always important to obtain your substances from a trusted source and to follow a strict schedule in order to improve the quality of your life!


This website does not promote or endorse the cultivation or use of psilocybin mushrooms. Psilocybin can be illegal and pose health risks. Always check your local laws and consult a medical professional before considering psilocybin use. Content is designed for adults aged 18 and over.

  • Not Healthcare Advice: Consult healthcare professionals for any medical concerns. We do not offer medical advice.
  • Legal Awareness: Users are responsible for knowing and adhering to the laws regarding magic mushrooms in their jurisdiction. We do not endorse illegal activities.
  • Risk Awareness: Psychedelic fungi carries potential risks. Information on our site is based on research and user experiences but should not replace professional advice.
  • Accuracy and External Links: We strive for accuracy but cannot guarantee it. External links are not under our control, and we are not responsible for their content.

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Unlock the secrets of the magical world of mushrooms with 'The Ultimate Magic Mushroom Strain Guide'. Learn all about the different psilocybin mushroom strains nature has to offer.



1UpMaps is a community resource that serves as a one-stop-shop for credible information, including a strain library as well as products and doctors/healers who are able to offer trip sitting during or integration therapy after an experience.

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